Corporate
Responsibility

Our corporate responsibility program

At Ultragenyx, our corporate responsibility strategy helps us identify, manage and communicate on topics relevant to our business and stakeholders and is structured around six key pillars:

  • Innovation
  • Patients
  • People
  • Communities
  • Planet
  • Governance

By focusing on these pillars, we strive to make a meaningful difference in the lives of those affected by rare and ultra-rare diseases.

To learn more about our corporate responsibility priorities,download the Materiality Assessment

Our 2025 Impact Report

2025 Ultragenyx Impact Report
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Our 2025 Impact Report covers our approach to corporate responsibility and highlights our ongoing commitment to transparency.

The report details our:

  • Innovative approach to drug development
  • Efforts towards providing equitable access to our medicines and improved care for people impacted by the rare diseases we study
  • Commitment to creating an inclusive workplace culture
  • Philanthropic support for community initiatives
  • Efforts to reduce our environmental footprint
  • Emphasis on strong corporate governance and a culture of integrity

Our strategic pillars

Pioneering new approaches to drug development for rare and ultra-rare diseases.

Commitment

We are a next-generation rare disease company committed to developing and delivering transformative treatments where none typically exist.

Innovation Icon
>230

participants representing more than 140 organizations have attended our Rare BootcampTM since 2017.

>160

locations with clinical studies across 19 countries as of Dec. 31, 2025.

~62%

of operating expenses were spent on R&D in 2025.

Propelling the entire rare disease community forward to transform as many lives as possible

Commitment

We are committed to supporting the rare disease community through our efforts to develop novel therapies, share our science and expertise, achieve broad access to screening and treatment, and partner with policymakers for meaningful change.

Patients Icon
>700

patients in 50 countries have been approved for access to Ultragenyx treatments through various global expanded access and patient assistance programs since 2013.

>45

patient advocacy conferences, meetings and town halls attended worldwide in 2025.

27

global listen and learn sessions convened with rare disease communities to collect actionable feedback and inform strategies across 8 programs.

Sustaining and strengthening our generous and inclusive culture while enhancing our health and safety practices

Commitment

We are committed to working to maintain an inclusive, safe and healthy environment. We are also committed to fair and equitable compensation practices that are transparent and free from bias.

People Icon
>80

employee learning & development workshops in 2025.

86%

employee engagement score in 2025.*

40

students hosted across our Emerging Talent programs in 2025.

*A subset of the employee engagement survey—focused on employee pride in our company, whether an employee would recommend Ultragenyx as a good place to work, whether an employee experiences a feeling of personal accomplishment from their work and the employee’s intent to remain with us—is used to calculate an employee engagement score.

Aligning our corporate philanthropic efforts with our mission and purpose

Commitment

We are committed to supporting initiatives that provide meaningful impact for the rare disease community, public health and access to care, Science, Technology, Engineering, Arts and Mathematics (STEAM) education, and local, at-risk communities.

Communities Icon
~$3.3M

in charitable donations, independent medical education and health-related grants across more than 20 countries approved in 2025.

2,800

volunteer hours recorded by eligible employees in 2025.

~40

service projects hosted around the world during our 3rd annual Days of Service in 2025.

Managing our environmental impact and promoting sustainability

Commitment

We are committed to implementing an environmental strategy that helps to minimize our environmental footprint across our business.

Planet Icon
100%

renewable electricity procured at our Novato, CA headquarters and Bedford, MA gene therapy manufacturing facility.

>60,000

pounds of laboratory waste diverted from incineration in 2025 through our recycling partnerships.

Inaugural

Climate Risk Assessment completed to identify actual and potential impacts of climate-related risks and opportunities in our business.

governance-img
Maintaining robust corporate governance and risk management and upholding high standards of honest and ethical business conduct

Commitment

The foundation of our purpose to lead the future of rare disease medicine is built upon our commitments to strong corporate governance, ethics and integrity, compliance, data protection and security and responsible procurement.

Governance Icon
Minimum stock ownership

requirements for our directors and named executive officers.

Zero

material data privacy breaches or known security breaches or incidents resulting in material impact to our operations in 2025.

Resources

Corporate Governance
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Ultragenyx Code of Conduct
Code of Conduct
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Comprehensive Compliance Program
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Ultragenyx Standard for Suppliers
Standard for Suppliers
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Human Rights Policy
Download
EHSS-Logo
Environmental, Health, Safety & Sustainability Policy
Download
Statement on Transparency in our Supply Chain and Modern Slavery
Download
Materiality Analysis and Definitions
Download
2025 SASB and GRI Indexes
Download
Awards and recognitions

Discover more about Ultragenyx:

Grants card

Grants and contributions

Ultragenyx supports initiatives that provide impactful resources for the rare disease community.

View grants and charitable contributions
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Partnerships

Learn about partnership opportunities with Ultragenyx.

Partner with us